Welcome To Chemical Consulting Network

    Oxycodone

    Oxycodone

    $225.74$670.21

    Buy oxycodone 10 mg painkillers online in the USA and Canada all states with overnight shipping. No Rx needs. No need for a prescription to buy oxycodone online with a discount. We have branded oxycodone pills without prescription with a huge discount.

    Delivery Duration:
    USA: 6 hours- 24 hours
    Canada: 1day – 2 Days
    International Delivery: 3days – 4 Days

    Simply the Best in stock

    Clear
    SKU: N/A Category: Tag:

    Description

    What is oxycodone?

    Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.3 It is currently indicated as an immediate release product for moderate to severe pain and as an extended-release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period. Label The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.5

    Oxycodone is most conventionally embraced by specialists to reduce directly genuine pain distress. Nevertheless, there’s expanding worry among medicinal experts over the risks of using these medications, especially when they are used for a long time.

    Uses: 

    Oxycodone is used to help relieve moderate to severe pain.
    Oxycodone belongs to a class of drugs known as opioid (narcotic) analgesics.
    It works in the brain to change how your body feels and responds to pain.

    Side Effects:

    Nausea and vomiting.
    Fatigue.
    Depression.
    Coughing.
    Diarrhea.
    Runny nose.
    Teary eyes.
    Sweating.

    Storage:

    Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. See also Warning section. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. For more details, read the Medication Guide, or consult your pharmacist or local waste disposal company.

    Medical interactions:

    The Medication interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Some products that may interact with this drug include certain pain medications (mixed opioid agonist/antagonists such as pentazocine, nalbuphine, butorphanol), naltrexone.

    Mechanism Action:

    Oxycodone acts as a weak agonist at mu, kappa, and delta-opioid receptors within the central nervous system (CNS). Oxycodone primarily affects mu-type opioid receptors, which are coupled with G-protein receptors and function as modulators, both positive and negative, of synaptic transmission via G-proteins that activate effector proteins.

    Binding of the opiate stimulates the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and CAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase.

    Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibited. Opioids such as oxycodone also inhibit the release of vasopressin, somatostatin, insulin, and glucagon.

    Opioids close N-type voltage-operated calcium channels (kappa-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (mu and delta receptor agonist). This results in hyperpolarization and reduced neuronal excitability. 

    Toxicity:

    Symptoms of overdose include respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, bradycardia, hypotension, and death.

    HOW SHOULD I TAKE OXYCODONE :

    If you are taking the Oxycodone extended-release tablets, swallow them whole; do not chew, break, divide, crush, or dissolve them. Do not presoak, lick or otherwise wet the tablet prior to placing in the mouth. Swallow each tablet right after you put it in your mouth.

    Buy Hydrocodone Online

    Additional information

    Select Quantity

    60 Pills, 90 Pills, 120 Pills, 180 Pills, 240 Pills