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Diclazepam (also known as Chlorodiazepam) is a synthetic depressant substance of the benzodiazepine chemical class that produces effects similar to diazepams, such as anxiety suppression, disinhibition, anticonvulsant, hypnotic, muscle relaxing, and amnesia when administered.
- It was first synthesized by Leo Sternbach and his team at Hoffman-La Roche in 1960.
- In animal models, it has a potency of approximately ten times that of diazepam, of which it is a structural analog.
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- It is basically a synthetic depressant substance that belongs to a chemical class of benzodiazepines and is related to diazepam in its properties.
- The benzodiazepines contain a basic benzene ring that is linked with a seven-membered diazepine ring, having two nitrogen constituents located at R1 and R4.
- Chemically, it has the same structure, instead of at the R1 position, it is replaced with a methyl group.
- The benzodiazepine ring is linked to a ring of 2-chlorinated phenyl at R5, and also a chlorine group is attached at R7 of the benzyl ring.
- The Diclazepam also contains a ketone group that is formed by the double bonding of oxygen group to diazepine ring at the R2 position
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